Prior to Tsinghua University

admin 2026-02-10 Publications 165 0

1.   Development of an Efficient Route to 2–Ethynylglycerol for the Synthesis of Islatravir.

Rummelt, S. M.; Qi, J.;* Chen, Y.; Dropinski, J. F.; Hughes, G.; Kuethe, J. T.; Li, D.; Maloney, K. M.; Margelefsky, E.; Mathew, R.; Muzzio, D. J.; Nawrat, C. C.; Newman, J. A.; Ouyang, H.; Patel, N. R.; Qiao, Z.; Shang, G.; Sirota, E.; Song, Z. J.; Tan, L.; Varsolona, R. J.; Wan, B.; Wyvratt, B. M.; Xu, F.; Xu, Y.; Yin, J.; Zhang, S.; Zhao, R. Org. Proc. Res. Dev. submitted.

2.   Macrocycle-Induced Modulation of Internuclear Interactions in Homobimetallic Complexes.

Thierer, L. M.; Brooks, S. H.; Weberg, A. B.; Cui, P.; Zhang, S.; Gau, M. R.; Manor, B. C.; Carroll, P. J.; Tomson, N. C.* Inorg. Chem. 202261, 6263–6280.

3.   Electrochemical Activation of Galactose Oxidase: Mechanistic Studies and Synthetic Application.

Zhang, S.; Ruccolo, S.;* Fryszkowska, A.; Klapars, A.; Marshall, N. M.; Strotman, N. A. ACS Catal. 202111, 7270–7280.

4.   Biocatalytic Oxidation of Alcohols Using Galactose Oxidase and a Manganese (III) Activator for The Synthesis of Islatravir.

Johnson, H. C.;* Zhang, S.; Fryszkowska, A.; Ruccolo, S.; Robaire, S. A.; Klapars, A.; Patel, N. R.; Whittaker, A. M.; Huffman, M. A.; Strotman, N. A. Org. Biomol. Chem. 202119, 1620–1625.

5.   Selective Electrochemical Oxidation of Functionalized Pyrrolidines

Deprez, N. R.;* Clausen, D. J.; Yan, J.-X.; Peng, F.; Zhang, S.; Kong, J.; Bai, Y. Org. Lett. 202123, 8834–8837.

6.   Interdependent Metal-Metal Bonding and Ligand Redox-Activity in a Series of Dinuclear Macrocyclic Complexes of Fe, Co, and Ni.

Xing, X.; Zhang, S.; Thierer, L. M.; Gau, M. R.; Carroll, P. J.; Tomson, N. C.* Dalton Trans. 202049, 7796-7806.

7.   Interdependent Metal-Metal Bonding and Ligand Redox-Activity in a Series of Dinuclear Macrocyclic Complexes of Fe, Co, and Ni.

Wang, Q.; Zhang, S.; Cui, P.; Weberg, A. B.; Thierer, L. M.; Manor, B. C.; Gau, M. R.; Carroll, P. J.; Tomson, N. C.* Inorg. Chem. 202059, 4200–4214.

8.   N–H Bond Formation at a Diiron Bridging Nitride.

Zhang, S.; Cui, P.; Liu, T.; Wang, Q.; Longo, T. J.; Thierer, L. M.; Manor, B. C.; Gau, M. R.; Carroll, P. J.; Papaefthymiou, G. C.; Tomson, N. C.* Angew. Chem. Int. Ed. 2020, 59, 15215–15219.

9.   Controlling P-C/C-H Bond Cleavage in Nickel Bis(diphosphine) Complexes: Reactivity Scope, Mechanism and Computations.

Zhang, S.#; Li, H.#; Appel, A. M.; Hall M. B.;* Bullock, R. M.* Organometallics 2020, 18, 3306–3314.

10.  Tuning Metal–Metal Interactions through Reversible Ligand Folding in a Series of Dinuclear Iron Complexes.

Zhang, S.; Wang, Q.; Thierer, L. M.; Weberg, A. B.; Gau, M. R.; Carroll, P. J.; Tomson, N. C.* Inorg. Chem. 201958, 12234-12244.

11.  Reversible Heterolytic Cleavage of the H-H Bond by Molybdenum Complexes: Controlling the Dynamics of Exchange Between Proton and Hydride.

Zhang, S.; Appel, A. M.; Bullock, R. M.* J. Am. Chem. Soc. 2017139, 7376–7387.

12.  Synthesis of Dibromo- and Tetrabromo-bipyrrolines and Their Corresponding 2,6-Diazasemibuvallene Derivatives.

Huang, Z.; Zhan, M.; Zhang, S.; Luo, Q.; Zhang, W.-X.;* Xi, Z.* Org. Chem. Front. 2017, 4, 1785-1788.

13.  Facile P-C/C-H Bond Cleavage Reactivity of Nickel Bis(diphosphine) Complexes.

Zhang, S.; Li, H.; Appel, A. M.; Hall M. B.;* Bullock, R. M.* Chem. Eur. J. 2016, 22, 9493–9497.

14.  Molybdenum Hydride and Dihydride Complexes Bearing Diphosphine Ligands with a Pendant Amine. Formation of Complexes With Bound Amines.

Zhang, S.; Bullock, R. M.* Inorg. Chem. 2015, 54, 6397–6409.

15.  Semibullvalene and Diazasemibullvalene: Recent Advances in the Synthesis, Reaction Chemistry, and Synthetic Applications.

Zhang, S.; Zhang, W.-X.; Xi, Z.* Acc. Chem. Res. 201548, 1823–1831.

16.  The Chemistry of Zirconacycles and 2,6-Diazasemibullvalenes: Synthesis, Structures, Reactions, and Applications in the Synthesis of Novel N-Heterocycles.

Zhang, S.* Springer: Berlin Heidelberg, 2015. (Springer Theses: Recognizing Outstanding Ph.D. Research)

17.  Synthesis of α,α,α′,α′-Tetrachloro‑Δ1‑bipyrrolines and 4,8-Dichloro-2,6-diazasemibuvallenes

Zhan, M.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Org. Lett. 2015, 17, 1026–1029.

18.  Efficient Synthesis of Aza-triquinacene Derivatives via Cycloaddition of 2,6-Diazasemibullvalenes with Nitroso Compounds.

Zhan, M.; Zhang, S.; Huang, Z.; Xi, Z.* Chem. Asian. J. 201510, 862-864.

19.  Coordination-Induced Skeletal Rearrangements of Zirconacyclobutene-Silacyclobutene Fused Complexes.

Zhao, J.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Coord. Chem. Rev. 2014, 270–271, 2–13.

20.  Reaction of Titanacyclobutene-Silacyclobutene Fused-Ring Complexes with Nitriles via Formal Insertion of the C-N Triple Bond of Nitrile into the Silacyclobutene Ring.

Zhao, J.; Zhang, S.; Zhang, W.-X.;* Xi, Z.* Organometallics 201433, 8–11.

21.  Organo-di-Lithio Reagents: Cooperative Effect and Synthetic Applications.

Zhang, S.; Zhang, W.-X.; Xi, Z.* Top. Organomet. Chem. 201447, 1-42.

22.  Diastereoselective Nucleophilic Ring-Opening Reactions of 2,6-Diazasemibullvalenes for the Synthesis of Diverse Functionalized Δ1-Bipyrroline Derivatives.

Zhang, S.; Zhan, M.; Zhang, W.-X.; Xi, Z.* Chem. Eur. J. 201420, 9744-9752.

23.  Synthesis of Semibullvalene Derivatives via Co2(CO)8-Mediated Cyclodimerization of 1,4-Dilithio-1,3-butadienes.

Zhang, S.#; Zhan, M.#; Wang, Q.; Wang, C.; Zhang, W.-X.; Xi, Z.* Org. Chem. Front. 20141, 130-134.

24.  3-D Brickwall Polymeric Structure of TMEDA-Supported 1,4-Dilithio-1,3- Butadiene.

Zhang, S.; Zhan, M.; Zhang, W.-X.;* Xi, Z.* Organometallics 201332, 4020-4023.

25.  Oxidation of C-H bonds to C=O bonds by O2 only or N-oxides and DMSO: Synthesis of Δ1-bipyrrolinones and pyrrolino[3,2-b]pyrrolinones from 2,6-diazasemibullvalenes.

Zhang, S.; Zhan, M.; Luo, Q.; Zhang, W.-X.; Xi, Z.* Chem. Commun. 201349, 6146-6148.

26.  Lewis Acid-Catalyzed Site-Selective Cycloadditions of 2,6-Diazasemibullvalenes with Isocyanides, Azides and Diazo Compounds: Novel Reaction Patterns Leading to Diaza- and Triaza-Brexadiene Derivatives.

Zhang, S.; Zhang, W.-X.; Xi, Z.* Angew. Chem. Int. Ed. 2013523485-3489.

27.  Diazo Compounds as Electrophiles to React with 1,4-Dilithio-1,3-dienes: Efficient Synthesis of 1-Imino-Pyrrole Derivatives.

Zhan, M.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Org. Lett. 201315, 4182–4185.

28.  Reactivity of Seven-membered Azazirconacycloallenes and Four-membered Zirconacycles towards Diphenylacetonitrile.

Zhao, J.; Zhang, S.; Zhang, W.-X.;* Xi, Z.* Organometallics 201237, 8370-8374.

29.  Synthesis of Benzothieno[2,3-b]thiophenes, [2,3-b:3',2'-d]-dithienothiophenes and Their Selenium Derivatives via Electrophilic Cyclization and McMurry Cyclization.

Geng, W.; Wang, Z.; Wang, H.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Tetrahedron 201268, 5283-5289.

30.  2,6-Diazasemibullvalenes: Synthesis, Structural Characterization, Theoretical Analysis and Reaction Chemistry.

Zhang, S.; Wei, J.; Zhan, M.; Luo, Q.; Wang, C.; Zhang, W.-X.; Xi, Z.* J. Am. Chem. Soc. 2012134, 11964–11967. (Selected as JACS SpotlightJ. Am. Chem. Soc. 2012134, 13533-13534.)

31.  One-pot Synthesis of Pyrrolo[3,2-d]pyridazines and Pyrrole-2,3-diones via Zirconocene-mediated Four-component Coupling of Si-tethered Diyne, Nitriles and Azide.

Zhang, S.; Zhao, J.; Zhang, W.-X.; Xi, Z.* Org. Lett. 201113, 1626-1629.

32.  One-Pot Selective Syntheses of 5-Azaindoles through Zirconocene-Mediated Multicomponent Reactions with Three Different Nitrile Components and One Alkyne Component.

Zhang, S.; Zhang, W.-X.; Zhao, J.; Xi, Z.* Chem. Eur. J. 201117, 2442-2449.

33.  Palladium-catalyzed Synthesis of Benzosilolo[2,3-b]indoles via Cleavage of C(sp3)-Si Bond and Consequent Intramolecular C(sp2)-Si Coupling.

Liang, Y.; Zhang, S.; Xi, Z.* J. Am. Chem. Soc. 2011133, 9024-9027.

34.  Zirconocene and Si-Tethered Diynes: A Happy Match Directed toward Organometallic Chemistry and Organic Synthesis.

Zhang, W.-X.; Zhang, S.; Xi, Z.* Acc. Chem. Res. 201144, 541-551.

35.  Formation of Zirconocenes Containing Vinyl-imine and Keteniminate Species from Zirconacycles and Diphenylacetonitrile.

Zhao, J.; Zhang, S.; Zhang, W.-X.;* Xi, Z.* Organometallics 201130, 3464-3467.

36.  SiMe3-Substituted 1,3-Butadienes for the Diels-Alder Reaction, the Ene reaction, and the Allylation Reaction.

Zhao, F.; Zhang, S.; Xi, Z.* Chem. Commun. 201147, 4348-4357.

37.  Synthesis of Benzothiophene Derivatives from Dilithio Reagents, Sulfur, and Electrophiles via Electrophilic Cyclization.

Wang, Z.; Geng, W.; Wang, H.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Tetrahedron Lett. 201152, 6997-6999.

38.  Iterative Dianion Relay Along the Ring: Formation of gem-Bis(trimethylsilyl) Cyclopentenones from 2,5-Bis(trimethylsilyl) Oxy-cyclopentadienyl Dianions and Acid Chlorides.

Li, H.; Liu, L.; Wang, Z.; Zhao, F.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Chem. Eur. J. 201117, 7399-7403.

39.  One-Pot Synthesis and Unpredicted Hydrogen Bonds of the Guanidinium Triflates from Readily Available Amines, Carbodiimides, and Zn(OTf)2.

Li, D.; Wang, Y.; Zhang, W.-X.;* Zhang, S.; Guang, J.; Xi, Z.* Organometallics 201130, 5278-5283.

40.  Powerful Tools toward Complex Organic Molecules-Highlight on 2010 Nobel Prize on Chemistry.

Zhang, S.; Zhang, W.-X.* University Chem. 20106, 1-5.

41.  Cleavage and Reorganization of Zr−C/Si−C Bonds Leading to Zr/Si−N Organometallic and Heterocyclic Compounds.

Zhang, S.; Zhang, W.-X.; Zhao, J.; Xi, Z.* J. Am. Chem. Soc. 2010132, 14042-14045.

42.  Efficient One-Pot Synthesis of N-Containing Heterocycles by Multicomponent Coupling of Silicon-Tethered Diynes, Nitriles, and Isocyanides through Intramolecular Cyclization of Iminoacyl-Zr Intermediates.

Zhang, S.; Zhang, W.-X.; Xi, Z.* Chem. Eur. J. 201016, 8419-8426. (VIP Paper)

43.  One-pot Multi-Component Synthesis of Azaindoles and Pyrroles from One Molecule of silicon-Tethered Diyne and Three or Two Molecules of Organonitriles Mediated by Zirconocence.

Zhang, S.#; Sun, X.#; Zhang, W.-X.; Xi, Z.* Chem. Eur. J. 200915, 12608-12617.

44.  Zirconium- and Silicon-Containing Intermediates with Three Fused Rings in a Zirconocene-Mediated Intermolecular Coupling Reaction.

Zhang, W.-X.; Zhang, S.; Sun, X.; Nishiura, M.; Hou, Z.;* Xi, Z.* Angew. Chem. Int. Ed. 200948, 7227-7231.

45.  Star-shaped Silacyclobutene-Containing π-Systems: Synthesis and Optical Properties.

Liu, J.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Organometallics 200928, 413-417.

46.  Reactivity of Six-Membered Silacycles.

Zhang, S.; Liu, J.; Zhang, W.-X.; Xi, Z.* Prog. Chem. 200921, 1487-1493.

47.  Synthesis of Six-Membered Silacycles.

Liu, J.; Zhang, S.; Zhang, W.-X.; Xi, Z.* Prog. Chem. 200921, 1475-1486.






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